Completely broken when using LUI. Absolutely zero changes will save and it always loads the default setting on a UI reload. Last good working version with LUI is beta9.40011.1.
For me its been at least since 8.3, unsure of a version number, but its been a long time. Ive been taking to deleting the LUI line from the AddonSkins LUA file to fix it, which really more lets me use a custom profile finally.