I have the same problem with PitBull 41261... Even deleting all saved variables and starting from scratch didn't fix it (I first thought it was a problem with my saved variables which I've had since rev. 36xxx).
Additionally, I get: [i]Dewdrop-2.0: [nil] Missing "get" directive
every time I mouse over "Copy from other Frame" under Other -> Layout
and: [i]Interface\Addons\PitBull]\PitBull_MetaLayout.lua:2262: attempt to index local 'db' (a nil value)
when I mouse over "Choose".
Edit: Ok, seems the size not changing was a bug in Dewdrop that was fixed in the latest commit... however, the two error messages are still there ;)
Edit2: Actually there a *tons* of nil-errors when starting with empty saved vars.. literally every options dialog is throwing nil errors at me :(