This is my UI now, I just started playing WoW recently.
Amazingly enough that's not horrible. Other than alignment, which you mentioned is on your to-do list:
The StatBlocks/Fortress/whatever plugins are pretty messy all over the place.
Your buff icon border texture doesn't quite match your action button border texture.
Your action buttons could benefit from some state paging. For instance, why do you need bandages and heals showing while you're in cat form? I'd recommend you check out Buffet, which will create and update macros to give you potions while in combat, and food/water out of combat, as it's kind of pointless to have food/water buttons while you're in combat.
Other than that, you're using a single font and a single statusbar texture, and the whole thing is generally clean. It's a good start.