It isn't really hard or performance hitting for wow to run wow in fullscreen maximised windowed mode without the borders (the option is in game) and just alt-tab to twitter. There isn't any delay in alt-tabbing since its all windowed.
I lost at least 10-15 FPS running in a maximized window versus fullscreen under 32-bit WinXP. Under Win7 x64 RC1 on the same hardware there is no performance loss. This is the main reason I've been using Win7 as my primary OS lately (alt+tabbing out during the lulls in a raid is essential for staying awake :p).
And yeah, using /reloadui to get external data into WoW is retardedly clunky IMO.