I made BossWhisperer for this purpose, but then some dude came and totally fucked up the addon for me by rewriting it into a FuBar plugin and stuff. I'll fix that today by uploading a SimpleBossWhisperer addon or something.
Allright, i would have prefered a seperated bossblocker, as im currenctly most convenient with Deadly Bossmods.
Not saying there's an ultimate gain to DBM vs BigWigs in any direction, but I never understood why DBM is supposed to be so good. The only thing it got over BigWigs is the auto-reply during bossfights. Which one had for BigWigs with BossWhisperer until that addon's v2.0 upgrade broke it. :s